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The Beekeeping and Honeybees Forum is a great place to find beekeepers sites and information about how to keep bees and produce honey. Here you can keep up with the newest techniques for beekeeping and find resources for apiaran technology.
 

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Propolis Proven Cytotoxic on Colon Cancer Cells - 04/01/2013
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Rich in flavonoids, Propolis consistenly exhibits strong antioxidant, anti-inflammatory, antiviral, antifungal, anti-tumoral activity. This study effectively identifies the active flavonoids and phenolic acids which produced these positive results...  Chemical Composition, Cytotoxic and Antioxidative Activities of Ethanolic Extracts of propolis on HCT-116 Cell Line Journal of the Science of Food and Agriculture , 2013, Accepted Article Background : Propolis is a complex resinous sticky substance that honeybees collect from buds and exudates of various plants. Due to propolis versatile biological and pharmacological activities, it is widely used in medicine, cosmetics and food industry. The aim of this study was to evaluate cytotoxic and antioxidative effects of various ethanolic extracts of propolis (EEP) on human colon cancer cell line (HCT-116) and compare it with their composition. HPLC-DAD method was used to determine the chemical composition of propolis samples. Results : The most abundant flavonoids in all samples were chrysin, pinocembrin and galangin (12.697- 40.811 µg mg-1). On the other hand, main phenolic acids were caffeic, ferulic and isoferulic acid . Dose and time-dependent inhibition of cell growth of HCT-116 cells was observed in all propolis samples, with IC50 values ranging from 26.33 to 143.09 µg mL-1. Differences in cytotoxic activity of propolis samples were associated with differences in their composition. Our results showed that all EEP samples...

Propolis Proven Cytotoxic on Colon Cancer Cells



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