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Propolis Effective in Treating Vaginal Thrush - 01/25/2013
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Already recognized for its antifungal capacity, propolis is also effective in treating vaginal conditions. Propolis ovules have seen dramatic results, in and out of controlled studies. It's exciting to see this study confirm the anecdotal reports from patients and clients... Preparation and characterization of mucoadhesive thermoresponsive systems containing propolis for the treatment of vulvovaginal candidiasis J Pharmaceutical Sciences , 2013, Jan  18 Abstract This work describes the preparation and characterization of mucoadhesive thermoresponsive systems consisted of poloxamer 407 (P407), Carbopol® 934P (C934P), and propolis to treat vulvovaginal candidiasis (VVC). Systems were obtained with different percentages of P407 and C934P to deliver propolis, a potent drug against VVC . Temperature of gelation, hardness, compressibility, adhesiveness, elasticity, cohesiveness, mucoadhesion, rheology (continuous flow and oscillatory), in vitro drug release, and antimicrobial activity were evaluated. Increasing the polymer content or temperature and the drug presence significantly increased mechanical properties of formulations. These exhibited pseudoplastic flow and low degrees of thixotropy. In most samples, increasing the C934P content significantly changed the oscillatory rheological properties. Formulations showed thermoresponsive behavior, existing as a liquid at room temperature and gel at 34°C–37°C. Propolis release from formulations was controlled by phenomenon ...

Propolis Effective in Treating Vaginal Thrush



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