The Melanoma Assassin - Propolis possesses numerous bioflavonoids and Galangin is commonly found in Propolis from the Northern Hemisphere in areas with Poplar trees. Yet this anti-cancerous characteristic is consistently present with all Propolis, since there are other bioflavonoids which possess this capacity... Galangin Induces B16F10 Melanoma Cell Apoptosis Via Mitochondrial Pathway and Sustained Activation of p38 MAPK Cytotechnology , 2012 Sep 22 Galangin, an active flavonoid present at high concentration in Alpinia officinarum Hance and propolis , shows cytotoxicity towards several cancer cell lines, including melanoma . However, the specific cellular targets of galangin-induced cytotoxicity in melanoma are still unknown. Here, we investigated the effects of galangin in B16F10 melanoma cells and explored the possible molecular mechanisms. Galangin significantly decreased cell viability of B16F10 cells, and also induced cell apoptosis shown by Hoechst 333...